Skip to main content

Table 3 Effectors of M. oryzae

From: Arms and ammunitions: effectors at the interface of rice and it’s pathogens and pests

Effector Known function/related information References
Apoplastic effectors
SLP1 Competes with plant OsCEBiP to bind chitin oligosaccharides and helps the fungus suppress chitin-induced immunity in host; outlines IH, i.e. localised to EIHMx Mentlak et al. (2012), Giraldo et al. (2013)
BAS3 focused point localisation in EIHMx & accumulates in the regions where IH cross at the cell wall to neighbouring cells Mosquera et al. (2009)
BAS4 Outlines IH, i.e. localised to EIHMx Mosquera et al. (2009)
BAS113 Outlines IH, i.e. localised to EIHMx Giraldo et al. (2013)
MC69 Targeted gene disruption affects the pathogenicity of M. oryzae Saitoh et al. (2012)
MSP1 Secreted into apoplasm; induces cell death & elicits immune responses Wang et al. (2016c)
Cytoplasmic effectors
PWL1 Accumulate at BIC, translocate to rice cytoplasm Khang et al. (2010)
PWL2 Accumulate at BIC, translocate to rice cytoplasm, and move from cell to cell Khang et al. (2010)
BAS1 Accumulate at BIC Khang et al. (2010), Mosquera et al. (2009)
BAS2 Translocate to rice cytoplasm, and accumulate at cell wall crossing points Mosquera et al. (2009)
BAS107 Accumulates at BIC, translocates and localises to rice cell nucleus, also moves from cell to cell Giraldo et al. (2013)
Avr-Piz-t Translocates to rice cells; interacts with Avr-Piz-t Interacting Protein 6 (APIP6, RING E3 ubiquitin ligase), APIP10 (RING E3 ubiquitin ligase), APIP5(bZIP transcription factor), APIP12 (homologue of nucleoporin protein, Nup80), OsAKT1 (Potassium (K+) channel protein) and OsRac1(homologue of human small GTPase) to suppress PTI Park et al. (2012, 2016), Wang et al. (2016a), Tang et al. (2017), Shi et al. (2018), Bai et al. (2019)
Avr-Pii Interact with OsExo70-F3 (exocyst complex protein) and Os-NADP-ME2 (NADP-malic enzyme2) Fujisaki et al. (2015), Singh et al. (2016)
Avr-CO39 Translocates to rice cells; purified protein directly localises to protoplast without aid from fungal components, RAG5 interaction leads to recognition by RAG4/RAG5 R pair proteins Ribot et al. (2013), Cesari et al. (2013)
Avr-Pia RAG5 interaction leads to recognition by RAG4/RAG5 R pair proteins Cesari et al. (2013)
MoHEG13 Suppresses the cell death caused by MoNLP proteins Mogga et al. (2016)
MoHEG16 Necessary for successful virulence of M. oryzae Mogga et al. (2016)
IUG6 BIC localisation and suppression of salicylic acid & ethylene signalling Dong et al. (2015)
IUG9 BIC localisation and suppression of salicylic acid & ethylene signalling Dong et al. (2015)
Avr-Pita Predicted metalloprotease domain; binds to cognate R protein Pita directly; accumulates at BIC Jia et al. (2000)
Avr-Pik/km/kp The different alleles are pathogen race specific; have cognate functional R gene pair of NB-LRR with a set of Pik alleles in rice Yoshida et al. (2009), Kanzaki et al. (2012)
Avr-Pi9 Localises to BIC and translocate to rice cells Wu et al. (2015)
Avr-Pib   Zhang et al. (2015)
Avr-Pi54 Interacts directly with the R protein Pi54 Devanna et al. (2014)
Avr-Pi12   Li et al. (2018b)
Secondary metabolites as effector
Hydroxylated Jasmonic acid (12OH-JA) antibiotic biosynthesis monooxygenase (Abm) converts free jasmonic acid (JA) to Hydroxylated JA (12OH-JA) Patkar et al. (2015)
Unknown secondary metabolite Synthesis involves avirulence conferring enzyme 1, ACE1 an appressoria localised effector protein; the corresponding R gene is identified to be Pi33 Bohnert et al. (2004), Collemare et al. (2008)
Tenuazonic acid (TeA) TAS1 is involved in the synthesis of TeA Yun et al. (2015)
Cytokinin Known protein involved is cytokinin synthesis 1, CSK1 Chanclud et al. (2016)