Fig. 3

Effector secretory routes of M. oryzae. The fungal effector secretion takes place via vesicles and follows two routes. The BFA-insensitive vesicle secretion from endoplasmic reticulum (ER) which forms the BIC (1), which is destined for the plant cell cytoplasm, and the BFA-sensitive effector secretion, via Golgi apparatus, which is directed to the EIHMx (2). The effectors secreted to the EIHMx are the apoplastic effectors (violet pie shapes) and secretions from BIC are the cytoplasmic effectors (yellow pie shapes). The cytoplasmic effectors further localise to specific cell compartments such as the nucleus or plasmodesmata (3) or bind their target proteins (4), or have enzymatic activity, to compromise the plant cell and enable fungal growth. The plant cell cytoplasm is shown in green, bright yellow region represents BIC and BIC along with violet represents EIHMx or apoplasm