Table 2 Deletions out of frame (Out-frame), deletions that maintain reading frame (In-Frame) generated using SpCAS9, LbCPF1 and BE_nCAS9D10A expressed as % of total mutant alleles identified. A total of 60, 30 and 22 mutants alleles were identified for SpCAS9, LbCPF1 and BE_nCAS9D10A respectively (see also Fig. 3)