Fig. 2

Target regions of gene modification by genome editing technology. Regions targeted by genome editing and examples of gene modification shown in this review are summarized. The yellow line indicates the cis-regulatory element in the promoter region of a target gene. Light blue and white boxes indicate 5′ and 3′ untranslated regions of a target gene, respectively. Black and green boxes indicate coding regions of a target gene and a region corresponding to the functional domain of a translated protein, respectively. Solid and dotted lines indicate the target gene locus and the intron of the target gene, respectively