Figure 5

Illustration of the predicted secondary structures for SNP- and wild-type osa-miR399j (a), osa-miR394 (b), and osa-miR399b (c). The mature miRNAs are shaded in pink. The circle marks the SNP position. The three miRNAs are shown as typical examples for displaying the increased (ΔΔG = −6.90 kcal/mol), unchangeable (ΔΔG = 0.00 kcal/mol), and decreased stability of hairpin structures (ΔΔG = 6.56 kcal/mol) by SNP variations.